Rongtuan Lin Selected Research

RNA Virus Infections

1/2017	ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.
8/2015	Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists.
1/2013	Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity.
11/2009	The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation.
6/2007	The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
6/2006	Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.

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Rongtuan Lin Research Topics

Disease

28	Infections 01/2019 - 04/2002
23	Virus Diseases (Viral Diseases) 01/2018 - 03/2002
9	Neoplasms (Cancer) 01/2019 - 09/2002
9	Vesicular Stomatitis 01/2017 - 10/2004
8	Bites and Stings (Sting) 01/2018 - 06/2010
6	RNA Virus Infections 01/2017 - 06/2006
4	Prostatic Neoplasms (Prostate Cancer) 04/2014 - 03/2012
3	Dengue (Dengue Fever) 10/2017 - 04/2014
3	Human Influenza (Influenza) 08/2015 - 04/2006
3	Melanoma (Melanoma, Malignant) 11/2007 - 09/2002
2	COVID-19 12/2021 - 01/2021
2	Carcinoma (Carcinomatosis) 10/2015 - 12/2009
2	Hodgkin Disease (Hodgkin's Disease) 06/2006 - 02/2003
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 09/2019
1	Shock 01/2019
1	Malaria 01/2019
1	Zika Virus Infection 10/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2016
1	Inflammation (Inflammations) 01/2016
1	Chikungunya Fever 04/2014
1	Retroviridae Infections (Infection, Retrovirus) 12/2013
1	Encephalitis (Encephalitis, Rasmussen) 12/2013
1	B-Cell Lymphoma (Lymphoma, B Cell) 11/2013
1	Adenocarcinoma 11/2013
1	Pneumonia (Pneumonitis) 01/2013

Drug/Important Bio-Agent (IBA)

25	Antiviral Agents (Antivirals)IBA 12/2021 - 06/2002
18	InterferonsIBA 01/2018 - 04/2002
10	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2002
8	Transcription Factors (Transcription Factor)IBA 01/2017 - 09/2002
7	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 03/2002
7	Interferon Type IIBA 01/2017 - 08/2007
7	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 06/2009 - 06/2002
5	Viral RNAIBA 09/2019 - 01/2013
5	RNA Helicases (RNA Helicase)IBA 06/2007 - 02/2006
4	Phosphotransferases (Kinase)IBA 01/2017 - 05/2003
4	CytokinesIBA 10/2016 - 09/2002
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016 - 09/2002
4	Double-Stranded RNA (RNA, Double Stranded)IBA 11/2007 - 03/2003
4	NF-kappa B (NF-kB)IBA 06/2007 - 04/2002
3	RNA (Ribonucleic Acid)IBA 01/2017 - 08/2015
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2015 - 07/2006
3	Interferon Regulatory FactorsIBA 01/2011 - 04/2002
3	I-kappa B KinaseIBA 06/2009 - 10/2004
2	Pattern Recognition ReceptorsIBA 09/2019 - 01/2017
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2018 - 11/2009
2	sulforaphaneIBA 01/2018 - 01/2017
2	AntioxidantsIBA 01/2017 - 12/2014
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016 - 11/2009
2	Interleukin-6 (Interleukin 6)IBA 10/2015 - 09/2002
2	Androgen Receptors (Androgen Receptor)IBA 04/2014 - 03/2012
2	TNF Receptor-Associated Factor 3IBA 04/2013 - 11/2009
2	Messenger RNA (mRNA)IBA 11/2011 - 09/2002
2	Small Interfering RNA (siRNA)IBA 10/2011 - 11/2009
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2011 - 02/2006
2	Toll-Like Receptor 3IBA 03/2011 - 11/2007
2	Phospho-Specific AntibodiesIBA 12/2003 - 03/2003
2	ChemokinesIBA 09/2002 - 06/2002
2	Chemokine CCL5IBA 09/2002 - 06/2002
1	remdesivirIBA 12/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Phenformin (Fenformin)IBA 01/2021
1	beta-lapachoneIBA 01/2021
1	Cromolyn Sodium (Cromoglicic Acid)FDA LinkGeneric 01/2019
1	p-Methoxy-N-methylphenethylamineIBA 01/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019
1	LipidsIBA 01/2018
1	itaconic acidIBA 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 10/2017
1	A-Form DNA (A-DNA)IBA 01/2017
1	Interleukin-1 (Interleukin 1)IBA 01/2016
1	Insulin-Like PeptidesIBA 10/2015
1	LigandsIBA 10/2015
1	UridineIBA 08/2015
1	Oseltamivir (Tamiflu)FDA Link 08/2015
1	NADPH Oxidases (NAD(P)H oxidase)IBA 12/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2014
1	Vorinostat FDA Link 03/2014
1	Histone Deacetylase InhibitorsIBA 03/2014
1	Inositol (Myoinositol)IBA 02/2014
1	Diphosphates (Pyrophosphates)IBA 02/2014
1	factor AIBA 12/2013
1	Annexin A5IBA 11/2013
1	triptolideIBA 11/2013
1	Caspase 3 (Caspase-3)IBA 11/2013
1	theasinensin AIBA 11/2013
1	CREB-Binding ProteinIBA 09/2013
1	Etoposide (VP 16)FDA LinkGeneric 09/2013
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 04/2013
1	triphosphoric acid (triphosphate)IBA 01/2013
1	sharpinIBA 08/2012
1	Androgen Antagonists (Antiandrogens)IBA 03/2012
1	Histones (Histone)IBA 01/2012
1	histone deacetylase 3IBA 01/2012
1	LipopolysaccharidesIBA 10/2011

Therapy/Procedure

6	Therapeutics 12/2021 - 11/2006
2	Castration 04/2014 - 03/2012
1	Highly Active Antiretroviral Therapy (HAART) 01/2019
1	Intravenous Administration 01/2013